Cellenis® PRGF System: Product & Application Guide

What is the Cellenis® PRGF System?

The Cellenis® PRGF system is an autologous cellular treatment system built on a patented separator and permeable filter gel technology. It isolates platelets at the highest possible efficiency while eliminating unwanted components — red blood cells (RBC), leukocytes and neutrophils — that can negatively affect the healing process.

How it works

• Growth factors released by activated platelets stimulate the formation of new blood vessels (angiogenesis) in the target tissue.
• It strongly triggers tissue repair and new collagen synthesis, thickening the epidermis and improving skin texture, elasticity and tone.
• Thanks to a fast, safe and standardized centrifugation process, specialist physicians obtain a high concentration of biologically rich autologous cell replication.

Advantages of the Cellenis® PRGF System

• Outstanding cell recovery: Recovers 80% (±10%) of the platelets present in the blood sample, guaranteeing maximum growth factor yield.
• Fast and practical protocol: Ready for application after a single spin cycle and only 10 minutes of centrifugation.
• Patient comfort and safety: Requires only a minimal blood sample; a fully biological, pyrogen-free method with no additives or chemical modification.
• Excellent cost value: An 11 ml tube yields approximately 6 ml of pure PRP/PRGF; a 22 ml tube yields approximately 13 ml, minimizing the consumable cost per milliliter.
• Consistent, customizable concentration: Delivers stable, operator-independent results, with concentration adjustable up to 5X through plasma reduction.

Tissue Effects of Growth Factors

Tube Technology

• Vacuum-sealed sterile glass construction: Specially coated to prevent early platelet adhesion to the tube wall and premature degranulation.
• Modified anticoagulant formulation: Optimized acidity preserves platelet viability while eliminating the burning sensation typically felt during injection.
• Patented physical separator filter gel: Retains more than 80% of total platelet volume in the upper phase, traps 99.9% of red blood cells at the base (the resulting PRP is a pure golden-yellow color, not pink or red), and filters out 92–96% of pro-inflammatory neutrophils.

Cell Count & Growth Factor Statistical Analysis

The figures below reflect average data from independently validated laboratory tests and clinical analyses.

Clinical Application Protocols & Results

Classified as an FDA Class II and CE Class IIb certified medical device, the system offers clinics a standard, reliable and operator-independent workflow. Its physiological pH balance minimizes pain and inflammatory reactions during tissue injections.

Trichological (hair) applications

A protocol of 3 sessions applied at 4-week intervals produced a statistically significant increase in follicle density and hair shaft thickness in the treated area. In 5-session courses, high hair quality retention was observed even 6 months after the first application.

Dermatological and aesthetic skin applications

Micro-injection applications to the submental (chin) area showed noticeable tissue firming, elasticity improvement and tightening 3 months after treatment. In the treatment of acne scars and epidermal blemishes, visible improvement in skin smoothness and tone uniformity was observed as early as 2 months after the first application.